Publications

PubMed Link To All Publications:

http://www.ncbi.nlm.nih.gov/pubmed/?term=ostrowski+mc

Google Scholar Link To All Publications:

https://scholar.google.com/citations?user=xdIRtREAAAAJ&hl=en

Selected  Publications 2007-2015. 

Meisen WH, Dubin S, Sizemore ST, Mathsyaraja H, Thies K, Lehman NL, Boyer P, Jaime-Ramirez AC, Elder JB, Powell K, Chakravarti A, Ostrowski MC, Kaur B. Changes in BAI1 and nestin expression are prognostic indicators for survival and metastases in breast cancer and provide opportunities for dual targeted therapies.  Mol Cancer Ther. 2015 Jan;14(1):307-14. . Epub 2014 Nov 5. PMID:25376607

Mathsyaraja H, Thies K, Taffany DA, Deighan C, Liu T, Yu L, Fernandez SA, Shapiro C, Otero J, Timmers C, Lustberg MB, Chalmers J, Leone G, Ostrowski MC. CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth. Oncogene. 2014 Sep 22.  [Epub ahead of print]  PMID:25241894

Wallace JA*, Li F*, Balakrishnan S*, Cantemir-Stone CZ, Pecot T, Martin C, Kladney RD, Sharma SM, Trimboli AJ, Fernandez SA, Yu L, Rosol TJ, Stromberg PC, Lesurf R, Hallett M, Park M, Leone G, Ostrowski MC. Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer.  PLoS One. 2013 Aug 16;8(8):e71533. 2013. PMID:23977064 *Equal Contributors

Wolford CC, McConoughey SJ, Jalgaonkar SP, Leon M, Merchant AS, Dominick JL, Yin X, Chang Y, Zmuda EJ, O’Toole SA, Millar EK, Roller SL, Shapiro CL, Ostrowski MC, Sutherland RL, Hai T.  Transcription factor ATF3 links host adaptive response to breast cancer metastasis. J Clin Invest. 2013 Jul;123(7):2893-906.  Epub 2013 Jun 10. PMID:23921126

Bronisz A, Godlewski J, Wallace JA, Merchant AS, Nowicki MO, Mathsyaraja H, Srinivasan R, Trimboli AJ, Martin CK, Li F, Yu L, Fernandez SA, Pécot T, Rosol TJ, Cory S, Hallett M, Park M, Piper MG, Marsh CB, Yee LD, Jimenez RE, Nuovo G, Lawler SE, Chiocca EA, Leone G, Ostrowski MC. Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320. Nat Cell Biol. 2012 14(2):159-67. Epub 2011 Dec 18.  PMID:22179046

Wang H, Karikomi M, Naidu S, Rajmohan R, Caserta E, Chen HZ, Rawahneh M, Moffitt J, Stephens JA, Fernandez SA, Weinstein M, Wang D, Sadee W, La Perle K, Stromberg P, Rosol TJ, Eng C, Ostrowski MC, Leone G. Allele-specific tumor spectrum in pten knockin mice. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5142-7.  Epub 2010 Mar 1. PMID:20194734

Zabuawala T, Taffany DA, Sharma SM, Merchant A, Adair B, Srinivasan R, Rosol TJ, Fernandez S, Huang K, Leone G, Ostrowski MC. An ets2-driven transcriptional program in tumor-associated macrophages promotes tumor metastasis. Cancer Res. 2010 Feb 15;70(4):1323-33.  Epub 2010 Feb 9. PMID:20145133

Trimboli AJ*, Cantemir-Stone CZ*, Li F*, Wallace JA, Merchant A, Creasap N, Thompson JC, Caserta E, Wang H, Chong JL, Naidu S, Wei G, Sharma SM, Stephens JA, Fernandez SA, Gurcan MN, Weinstein MB, Barsky SH, Yee L, Rosol TJ, Stromberg PC, Robinson ML, Pepin F, Hallett M, Park M, Ostrowski MC, Leone G. Pten in stromal fibroblasts suppresses mammary epithelial tumours. Nature. 2009 Oct 22;461(7267):1084-91. PMID:19847259  *Equal Contributors

Pan F, Yu H, Dang EV, Barbi J, Pan X, Grosso JF, Jinasena D, Sharma SM, McCadden EM, Getnet D, Drake CG, Liu JO, Ostrowski MC, Pardoll DM. Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells. Science. 2009 Aug 28;325(5944):1142-6. doi: 10.1126/science.1176077. Epub 2009 Aug 20. PMID:19696312

Wei G*, Srinivasan R*, Cantemir-Stone CZ, Sharma SM, Santhanam R, Weinstein M, Muthusamy N, Man AK, Oshima RG, Leone G, Ostrowski MC. Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis. Blood. 2009 Jul 30;114(5):1123-30.  Epub 2009 May 1. PMID:19411629 *Equal Contributors

Aliprantis AO, Ueki Y, Sulyanto R, Park A, Sigrist KS, Sharma SM, Ostrowski MC, Olsen BR, Glimcher LH. NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism. J Clin Invest. 2008 Nov;118(11):3775-89.  Epub 2008 Oct 9. PMID:18846253

Trimboli AJ, Fukino K, de Bruin A, Wei G, Shen L, Tanner SM, Creasap N, Rosol TJ, Robinson ML, Eng C, Ostrowski MC, Leone G. Direct evidence for epithelial-mesenchymal transitions in breast cancer. Cancer Res. 2008 Feb 1;68(3):937-45. PMID:18245497

Sussan TE, Yang A, Li F, Ostrowski MC, Reeves RH. Trisomy represses Apc(Min)-mediated tumours in mouse models of Down’s syndrome. Nature. 2008 Jan 3;451(7174):73-5. PMID:18172498
Hu R*, Sharma SM*, Bronisz A, Srinivasan R, Sankar U, Ostrowski MC. Eos, MITF, and PU.1 recruit corepressors to osteoclast-specific genes in committed myeloid progenitors. Mol Cell Biol. 2007 Jun;27(11):4018-27. Epub 2007 Apr 2. PMID:17403896 *Equal Contributors
Sharma SM, Bronisz A, Hu R, Patel K, Mansky KC, Sif S, Ostrowski MC. MITF and PU.1 recruit p38 MAPK and NFATc1 to target genes during osteoclast differentiation. J Biol Chem. 2007 May 25;282(21):15921-9. Epub 2007 Apr 2. PMID:17403683
Meadows NA, Sharma SM, Faulkner GJ, Ostrowski MC, Hume DA, Cassady AI. The expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factor. J Biol Chem. 2007 Jan 19;282(3):1891-904. Epub 2006 Nov 14. PMID:17105730

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