Publications

Click Here for Google Scholar List

  1. Barnhouse, V., Weist, J.L., Shukla, V.C., Ghadiali, S.N., Kniss, D.A., Leight, J.L., Myoferlin regulates epithelial cancer cell plasticity and migration through autocrine TGF-β1 signaling, Oncotarget, in press, 2018
  2. *Shukla, V., *Kuang, T., Senthilvelan, A., Higuita-Castro, N., Duarte-Sanmiguel, S., Ghadiali, S.N., Gallego-Perez, D., Lab-on-Chip Platforms for Biophysical Studies of Cancer with Single-Cell Resolution, Trends in Biotechnology, in press, 2018.
  3. Malik, J. and Ghadiali, S.N., Multi-scale Modeling of an Upper Respiratory Airway: Effect of Mucosal Adhesion on Eustachian Tube Function in Young Children, Journal of Clinical Biomechanics, in press, 2018.
  4. Shukla, V., Barnhouse, V., Acherman IV, W.E., Summerfield, T.L., Powell, H.M., Leight, J.L., Kniss, D.A., Ghadiali, S.N., Cellular Mechanics of Primary Human Cervical Fibroblasts: Influences of Progesterone and a Pro-Inflammatory Cytokine, Annals of Biomedical Engineering, 46(1): 197-207, 2018. DOI: 10.1007/s10439-017-1935-0
  5. Higuita-Castro, N., Nelson, M.T., Shukla, V., Agudelo-Garcia, P.A., Zhang, W., Duarte-Sanmiguel, S.M., Lannutti, J.J., Englert, J.A., Hansford, D.J., Ghadiali, S.N., Using a Novel Microfabricated Model of the Alveolar-Capillary Barrier to Investigate the Effect of Matrix Structure on Atelectrauma, Scientific Reports, 7: 11623, 2017. DOI:10.1038/s41598-017-12044-9
  6. Hostnik E.T., Scansen, B.A., Zielinski, R., Ghadiali, S.N., Quantification of Nasal Airflow Resistance In English Bulldogs Using Computed Tomography and Computational Fluid Dynamics, Veterinary Radiology & Ultrasound, 58(5): 542-551, 2017. Doi:10.1111/vru.12531
  7. Hammer, A., Sizemore, G., Shukla, V., Avendano, A.., Sizemore, S., Chang, J., Kladney, R., Cuitino, M., Thies, K., Verfurth, Q., Chakravarti, A., Yee, L., Leone, G., Ghadiali, S.N., Song, J., Ostrowski, M., Stromal PDGFR-α activation enhances matrix stiffness, impedes mammary ductal development, and accelerates tumor growth, Neoplasia, 19(6): 496-508, 2017. Doi:10.1016/j.neo.2017.04.004
  8. Alper, C. M., Luntz, M., Takahashi, H., Ghadiali, S.N., Swarts, J.D., Teixeira, M., Csakanyi, Z., Yehudai, N., Kania, R., Poe, D. S., Panel 2: Anatomy (Eustachian Tube, Middle Ear and Mastoid – Anatomy, Physiology, Pathophysiology and Pathogenesis), Otolaryngology – Head and Neck Surgery, 156(4): S22-S40, 2017.
  9. Anstine L., Bobba, C., Ghadiali, S.N., Lincoln, J., Growth and maturation lead to altered mRNA profiles and impaired function of heart valve endothelial cells, Journal of Molecular and Cellular Cardiology, 100, 72-82, 2016.
  10. Higuita-Castro N., Shukla, V.C., Mihai, C., Ghadiali, S.N., Simvastatin Treatment Modulates Mechanically-Induced Injury and Inflammation in Respiratory Epithelial Cells, Annals of Biomedical Engineering, 44: 3632, 2016.
  11. Malik, J.E., Swarts, J.D., Ghadiali, S.N., Multi-scale Finite Element Modeling of Eustachian Tube Function: Influence of Mucosal Adhesion, International Journal for Numerical Methods in Biomedical Engineering, e02776, 2016.
  12. Shukla, V.C., Higuita-Castro, N., Nana-Sinkam, P., Ghadiali, S.N., Substrate Stiffness Modulates Lung Cancer Cell Migration but not Epithelial to Mesenchymal Transition, Journal of Biomedical Materials Research: Part A, 104A:1182-1193, 2016.
  13. Hayes Jr, D., Whitson, B.A., Ghadiali, S.N., Tobias, J.D., Mansour, H.M., Black, S.M., Influence of HLA mismatching on survival in lung transplantation, Lung, 193 (5): 789-797, 2015.
  14. Dowell J.D., Castle, J., Schickel, M., Andersson, K., McLoney, E., Guy, G., Yang, X., Ghadiali, S.N., Celect inferior vena cava wall strut perforation begets additional strut perforation: implications toward patient management, Journal of Vascular and Interventional Radiology, 26 (10): 1510-1518.e3, 2015.
  15. Hayes Jr, D., Whitson, B.A., Ghadiali, S.N., Lloyd, E.A., Tobias, J.D., Mansour, H.M., Black, S.M., Survival in Adult Lung Transplant Recipients Receiving Pediatric vs Adult Donor Allografts, Annals of Thoracic Surgery, 100 (4): 1211-6, 2015.
  16. Mathur A., Sizemore, G.M., Balakrishnan, S., Shukla, V.C., Cuitino, M., Trimboli, A.J., Ghadiali, S.N., Leone, G.W., Ostrowski, M.C., Stromal PDGFR-α activation stalls mammary ductal development and increases tumorigenic potential of mammary epithelia, Cancer Research 75 (15 Supplement), 985-985, 2015.
  17. Blackstone, B.N., Li, R., Ackerman, W.E., Ghadiali, S.N., Powell, H.M., Kniss, D.A., Myoferlin Depletion Elevates Focal Adhesion Kinase and Paxillin Phosphorylation and Enhances Cell-Matrix Adhesion in Breast Cancer Cells, American Journal of Physiology, Cell Physiology, 308: C642-C649, 2015.
  18. Nelson K, Bobba, C, Eren E, Spata T, Tadres, M, Hayes Jr, D., Black SM, Ghadiali S*, Whitson, BA*. Method of isolated ex-vivo lung perfusion in a Rat Model: Lessons Learned from Developing a Rat EVLP Program, Journal of Visualized Experiments, (96), e52309, 2015,*equal contributions
  19. Higuita-Castro, N., Mihai, C., Hansford, D.J., Ghadiali, S.N., Influence of airway wall compliance on epithelial cell injury and adhesion during interfacial flows, Journal of Applied Physiology, 117(11): 1231-1242, 2014.
  20. Kim, S.C., Kellett, T., Wang, S., Nishi, M., Nagre, N., Zhou, B., Flodby, P., Shilo, K., Ghadiali, S.N., Takeshima, H., Hubmayr, R.D., Zhao, X., Modulation of TRIM72 alters the repair capacity of lung epithelial cells, American Journal of Physiology: Lung Cell and Molecular Physiology, 307(6): L449-L450, 2014.
  21. Chen, X., Zielinski, R., Ghadiali, S.N., Computational Analysis of Microbubble Flows in Bifurcating Airways: Role of Gravity, Inertia and Surface Tension, Journal of Biomechanical Engineering, 136; 101007, 2014.
  22. Nelson K*, Bobba C*, Ghadiali S, Hayes Jr. D, Black SM, and Whitson BA. Animal models of ex vivo lung perfusion as a platform for transplantation research, World Journal of Experimental Medicine, 4(2); 7-15, 2014. *equal contributions
  23. Volakis, L.I., Li, R., Ackerman, W.E., Mihai, C., Bechel, M., Summerfiled, T.L., Ahn, C., Powell, H.M., Zielinski, R. Rosol, T.J., *Ghadiali, S.N., *Kniss, D.A., Loss of Myoferlin Redirects Breast Cancer Cell Motility Towards Collective Migration, PLoS One, 9(2): e86110, 2014. *equal contributions
  24. Zielinski, R., Mihai, C., Kniss, D.A., Ghadiali, S.N., Finite Element Analysis of Traction Force Microscopy: Influence of Cell Mechanics, Adhesion and Morphology, Journal of Biomechanical Engineering, 135(7), p. 71009-9, 2013.
  25. Ma, X., Weber, M., Stevenson, M.D., Sarang-Sieminki, A.L., Gooch, K.J., Ghadiali, S.N., Hart, R.T., Fibers in the Extracellular Matrix Enable Long-Range Stress Transmission Between Cells, Biophysical Journal, 104(7) pp. 1410 – 1418, 2013.
  26. Swarts, J.D., Alper, C.M., Luntz, M., Bluestone, C.D., Doyle, W.J., Ghadiali, S.N., Poe, D.S., Takahashi, H., Tideholm, B., Panel 2: Eustachian Tube, Middle Ear, and Mastoid: Anatomy, Physiology, Pathophysiology, and Pathogenesis, Otolaryngology – Head and Neck Surgery, 148(4S) E26–E36, 2013.
  27. Sheer, F.J., Swarts, J.D., Ghadiali, S.N., Three-dimensional finite element analysis of Eustachian tube function under normal and pathological conditions, Medical Engineering & Physics, 34: 605-616, 2012.
  28. Mihai C., Bao, S., Lai, J.P., Ghadiali, S.N., Knoell, D.L., PTEN inhibition improves wound healing in lung epithelia through changes in cellular mechanics that enhance migration, American Journal of Physiology: Lung Cell and Molecular Physiology, 302(3): L287-L299, 2012. (Featured Article)
  29. Huang, Y., Crawford, M., Higuita-Castro, N., *Nana-Sinkam, P., *Ghadiali, S.N., MiR-146a Regulates Mechanotransduction and Pressure-Induced Inflammation in Small Airway Epithelium, FASEB Journal, 26:3351-3364, 2012. *equal contributions
  30. Li, R., Ackerman, W.E., Mihai, C., Volakis, L.I., Ghadiali, S.N., Kniss, D.A., Myoferlin Depletion in Breast Cancer Cells Promotes Mesenchymal to Epithelial Morphology and Stalls Invasion: Role of MMP-1, PLoS One, 7(6): e39766, 2012.
  31. Ghadiali, S.N., Huang, Y., The role of airway recruitment and derecruitment in lung injury, Critical Reviews in Biomedical Engineering, 39(4): 297-318, 2011.
  32. Mengistu, M., Brotzman, H., Ghadiali, S.N., Lowe-Krentz, L., Fluid Shear Stress-Induced JNK Activity Leads to Actin Remodeling for Cell Alignment, Journal of Cell Physiology, 226(1): 110-121, 2011.
  33. Huang, Y., Haas, C., Ghadiali, S.N., Influence of Transmural Pressure and Cytoskeletal Structure on NF-κB Activation in Respiratory Epithelial Cells, Cellular and Molecular Bioengineering, 3(4): 415-427, 2010.
  34. Ghadiali, S.N., Bell, E.D., Swarts, J.D., Timing of Tensor and Levator Veli Palatini Force Applications Determines Eustachian Tube Active Resistance Patterns during the Forced Response Test, Auris Nasus Larynx, 37(6): 720-729, 2010.
  35. Sheer, F.J, Swarts, J.D., Ghadiali, S.N., Finite Element Analysis of Eustachian Tube Function in Cleft Palate Infants Based on Histological Reconstructions, Cleft Palate Craniofacial Journal, 47(6): 600-610, 2010.
  36. Dailey, H.L., Ghadiali, S.N., Influence of Power Law Rheology on Cell Injury During Microbubble Flows, Biomechanics and Modeling in Mechanobiology, 9(3): 263-79, 2010. PMID: 19865840
  37. *Yalcin, H.C., *Hallow, K.M., Wang, J., Ou-Yang, H.D., Ghadiali, S.N., Influence of Cytoskeletal Structure and Mechanics on Epithelial Cell Injury during Cyclic Airway Reopening, American Journal of Physiology: Lung Cell and Molecular Physiology, 297: L881-L891, 2009. *equal contributions
  38. Ghadiali, S.N., Invited Editorial: Making “Time” for Alveolar Recruitment, Journal of Applied Physiology, 106: 751-752, 2009.
  39. Dailey, H.L., Ricles, L.M., Yalcin, H.C., Ghadiali, S.N., Image-Based Finite Element Modeling of Alveolar Epithelial Cell Injury during Airway Reopening, Journal of Applied Physiology, 106: 221–232, 2009.
  40. Ghadiali, S.N. & Gaver, D.P., Biomechanics of Liquid-Epithelium Interactions in Pulmonary Airways, Respiratory Physiology and Neurobiology, 163: 232-243, 2008. (invited review for special issue on Respiratory Biomechanics)
  41. Wei, M.T., Zaorski, A., Yalcin, H.C., Wang, J., Hallow, M., Ghadiali, S.N., Chiou, A., Ou-Yang, H.D., A Comparative Study of Living Cell Micromechanical Properties by Oscillatory Optical Tweezers, Optics Express, 16: 8594-8603, 2008.
  42. Yalcin, H.C., Perry, S.F., Ghadiali, S.N., Influence of Airway Diameter and Cell Confluence on Epithelial Cell Injury in an In-Vitro Model of Airway Reopening, Journal of Applied Physiology, 103:1796-1807, 2007.
  43. Dailey, H.L. & Ghadiali, S.N., Fluid-Structure Analysis of Microparticle Transport in Deformable Pulmonary Alveoli, Journal of Aerosol Science, 38: 269-288, 2007.
  44. Dailey, H.L., Yalcin, H.C., Ghadiali, S.N., Fluid-Structure Modeling of Flow-Induced Alveolar Epithelial Cell Deformation, Computers and Structures, 85: 1066-1071, 2007.
  45. Bluestone, C.D., Alper, C.M., Buchman, C.A., Felding, J.U., Ghadiali, S.N., Hebda, P.A., Sando, I., Stangerup, S.E., Swarts, J.D., Takahashi, H., Eustachian tube, middle ear, and mastoid anatomy; Physiology, pathophysiology, and pathogenesis, Annals of Otology, Rhinology and Laryngology, 114: 16-30 Part 2 Suppl. 194, 2005.
  46. Kanick, S.C., Doyle, W.J., Ghadiali, S.N., Federspiel, W.J., On morphometric measurement of oxygen diffusing capacity in middle ear gas exchange, Journal of Applied Physiology, 98: 114-119, 2005.
  47. Ghadiali, S.N., Banks, J.D. Swarts, Finite Element Analysis of Active Eustachian Tube Function, Journal of Applied Physiology, 97: 648-654, 2004.
  48. Ghadiali, S.N., J. D. Swarts, W. J. Doyle, Effect of Tensor Veli Palatini Muscle Paralysis on Eustachian Tube Mechanics, Annals of Otology, Rhinology and Laryngology, 112(8): 704-711, 2003.
  49. Ghadiali, S.N., Gaver, D.P. III. The Influence of Non‑Equilibrium Surfactant Dynamics on the Flow of a Semi‑Infinite Bubble in a Rigid Cylindrical Capillary Tube. Journal of Fluid Mechanics, 478: 165-196, 2003.
  50. Ghadiali, S.N., J. Banks, J. D. Swarts, The Effect of Surface Tension and Surfactant Administration on Eustachian Tube Mechanics, Journal of Applied Physiology, 93: 1007-1014, 2002.
  51. Ghadiali, S.N., J.D. Swarts, W.J. Federspiel. Model-based Evaluation of Eustachian Tube Mechanical Properties Using Continuous Pressure-Flow Rate Data. Annals of Biomedical Engineering, 30: 1064-1076, 2002.
  52. Ghadiali, S.N., W.J. Federspiel, J.D. Swarts, W.J. Doyle. Measurement of the Viscoelastic Compliance of the Eustachian Tube Using a Modified Forced-Response Test. Auris Nasus Larynx, 29: 1-5, 2002.
  53. Ghadiali, S.N., D. Halpern and D.P. Gaver III. A Dual‑Reciprocity Boundary Element Method for Evaluating the Bulk Convective Transport of Surfactant in Free‑Surface Flows. Journal of Computational Physics, 171: 534-559, 2001.
  54. Ghadiali, S.N. and Gaver, D.P. III An Investigation of Pulmonary Surfactant Physicochemical Behavior under Airway Reopening Conditions. Journal of Applied Physiology, 88: 493-506, 2000.

Leave a Reply

Your email address will not be published. Required fields are marked *